Publications
2025
Vuong L.M., Hachey S., Shiu J., Xie D.F., Salvador N., Brindani N., Bertozzi S.M., Summa M., Bertorelli R., Armirotti A., Pham R., Ku V.S.H., Limbekar S.D., Nguyen T., Choi B., Hughes C.C.W., De Vivo M., Ganesan A.K.
CDC42-effector interaction inhibitors alter patterns of vessel arborization in skin and tumors in vivo
iScience, vol. 28, (no. 7)
2025
Montani C., Iovino L., Di Vetta F., Pasquin Mariani J. C. R., De Guzman A. E., Gini S., Galbusera A., DEpifanio B., Ghirardini E., Cornuti S., Dadà L., Putignano E., Alessandrì M. G., Vasirani G., Bertozzi S. M., Armirotti A., Baroncelli L., Gozzi A.
Connectomic and behavioural alterations in creatine transporter deficiency are partially normalized by gene therapy
Brain
2025
Economou C.N., Bertozzi S.M., Nardi M., Paul U.C., Fiorentini F., Ferrari G., Contardi M., Armirotti A., Fragouli D., Athanassiou A.
Enhanced biodegradation of polylactic acid by Aspergillus oryzae lipase: Toward sustainable plastic end-of-life solutions
Bioresource Technology, vol. 434
2025
Economou C. N., Bertozzi S. M., Nardi M., Paul U., Fiorentini F., Ferrari G., Contardi M., Armirotti A., Fragouli D., Athanassiou A.
Enzymatic degradation of polylactic acid films and microparticles with lipase enzyme from Aspergillus oryzae
8th International Conference on Multifunctional, Hybrid and Nanomaterials, 3-6 March 2025, Montpellier, France
Conference Paper
Conference
2025
Squarzoni A., Boschetti G., Bertozzi S.M., Summa M., Serani A., Milandri E., Mandrioli R., Protti M., Mercolini L., Montani C., Capodivento G., Cangemi G., Pedemonte N., Bandiera T., Benfenati F., Nobbio L., Bertorelli R., Armirotti A.
Exposure of dams to Elexacaftor/ Tezacaftor/Ivacaftor during pregnancy and breastfeeding induces reversible alterations in newborn wild type CD-1 mice
Journal of Cystic Fibrosis
2025
Economou C.N., Bertozzi S.M., Ferrari G., Armirotti A., Fragouli D., Athanassiou A.
Pleurotus ostreatus-Mediated Bioremediation of Polylactic Acid Microplastics: Unveiling a Sustainable Solution
ACS Omega, vol. 10, (no. 49), pp. 60945-60954
2025
Di Martino R.M.C., Russo D., Penna I., Demuro S., Dalle Vedove A., Spagnuolo R., Ottonello G., Bertozzi S.M., Summa M., Desantis J., Valeri A., Pruccoli L., Tripathi S.K., Tarozzi A., Storici P., Girotto S., Bertorelli R., Armirotti A., Cruciani G., Bandiera T., Cavalli A., Bottegoni G.
Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies
European Journal of Medicinal Chemistry, vol. 297
2025
Brindani N., La Serra M.A., Ortega J.A., Arencibia J.M., Nigro M., Bertozzi S.M., Armirotti A., Borgogno M., Sissi C., De Vivo M.
Tetrahydropyrido[4,3-d]pyrimidines as a new active scaffold for human topoisomerase II inhibitors
Scientific Reports, vol. 15, (no. 1)
2025
Rizzo M., Ferrera M., Pelli Cresi J.S., Mandrup Bertozzi S., Griesi A., Goldoni L., Kriegel I., Ferri M., Manna L.
Yet Another UREAlity Check: Compliant Analytical Tools, Electrochemical Insights, and Cell Configuration Effects in Urea Electrosynthesis on Polycrystalline Cu Electrodes
ACS Energy Letters, pp. 3580-3585
2024
Montani C., Galbusera A., D'Epifanio B., Ghirardini E., Cornuti S., Pasquin Mariani J.R., De Guzman E., Mandrup Bertozzi S., Armirotti A., Baroncelli L., Gozzi A.
Connectomic and behavioral alterations in creatine transporter deficiency are partially normalized by gene therapy
Biorxiv
2024
Brindani N., Vuong L.M., La Serra M.A., Salvador N., Menichetti A., Acquistapace I.M., Ortega J.A., Veronesi M., Bertozzi S.M., Summa M., Girotto S., Bertorelli R., Armirotti A., Ganesan A.K., De Vivo M.
Discovery of CDC42 Inhibitors with a Favorable Pharmacokinetic Profile and Anticancer In Vivo Efficacy
Journal of Medicinal Chemistry, vol. 67, (no. 12), pp. 10401-10424
2024
Ciobanu D.Z., Liessi N., Tomati V., Capurro V., Bertozzi S.M., Summa M., Bertorelli R., Loberto N., Dobi D., Aureli M., Nobbio L., Bandiera T., Pedemonte N., Bassi R., Armirotti A.
Tezacaftor is a direct inhibitor of sphingolipid delta-4 desaturase enzyme (DEGS)
Journal of Cystic Fibrosis
2023
Brindani N., Vuong L.M., Acquistapace I.M., La Serra M.A., Ortega J.A., Veronesi M., Bertozzi S.M., Summa M., Girotto S., Bertorelli R., Armirotti A., Ganesan A.K., De Vivo M.
Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer
Journal of Medicinal Chemistry, vol. 66, (no. 8), pp. 5981-6001
2023
Basagni F., Ortega J.A., Bertozzi S.M., Armirotti A., Summa M., Bertorelli R., Bartolini M., Mellor I.R., Bedeschi M., Bottegoni G., Lembo V., Minarini A., Cavalli A., Rosini M.
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties
European Journal of Medicinal Chemistry, vol. 261
2023
Bellina F., Berti F., Bertozzi S. M., Bandiera T., Bertozzi F.
Highly diastereoselective Heck-Matsuda reaction with pyrazolyl diazonium salts
New Journal of Chemistry
Article in Press
Journal
2023
Scarpelli R., Palomba M., Vecchio D., Ottonello G., Mandrup Bertozzi S., Summa M., Armirotti A., Bertorelli R., De Mei C., Grimaldi B.
Identification of a dual REV-ERBβ and autophagy inhibitor with in vivo anticancer efficacy (P222)- September 3-7, 2023, Zagreb (Croatia)
IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
Poster
Conference
2023
Stuefer A., Balasco L., Gini S., Coletta L., Rocchi F., Montani C., Alvino F.G., Sastre D., Galbusera A., Aldrighetti M., Mandrup Bertozzi S., Lau Poui Cheung P., Vozzi D., Papaleo F., Iurilli G., Armirotti A., Cancedda L., Lombardo M., Bozzi Y., Gozzi A.
Transient neocortical excitatory / inhibitory imbalance during early infancy leads to permanent social impairments
Neurobiology of social behaviors
Poster
Conference
2022
Tuccinardi D., Di Mauro A., Lattanzi G., Rossini G., Monte L., Beato I., Spiezia C., Bravo M., Watanabe M., Soare A., Kyanvash S., Armirotti A., Bertozzi S.M., Gastaldelli A., Pedone C., Khazrai Y.M., Pozzilli P., Manfrini S.
An extra virgin olive oil-enriched chocolate spread positively modulates insulin-resistance markers compared with a palm oil-enriched one in healthy young adults: A double-blind, cross-over, randomised controlled trial
Diabetes/Metabolism Research and Reviews, vol. 38, (no. 2)